• Any abnormality causing a loss of function in the

  2019-04-26

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Worldwide one in three women experience

  2019-04-26

  

  Worldwide, one in three women experience gender-based violence, which imparts physical, mental, and sexual health morbidities. It also causes mortality—more than a third of homicides of women are attributable to male partners. These data justifiably create global outrage, accentuated by horrific rec

• INNO-406 Esto es visible no s lo en las notas necrol

  2019-04-26

  

  Esto es visible no sólo en las notas necrológicas, sino también en los discursos que homenajean INNO-406 alguien en ocasión de su retiro o jubilación. En ellos encontramos rasgos comunes con las notas necrológicas, sobre todo en la idea de una herencia que deja el que se va, y que consiste en la tra

• br Clinical characteristics Brugada syndrome is more common

  2019-04-26

  

  Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn

• The circadian variation of VF

  2019-04-26

  

  The circadian variation of VF shows a similar nocturnal pattern in patients with BS and ERS [32] (Fig. 2). This is in contrast to the circadian pattern of VTAs in patients with ischemic heart diseases [33]. In a Korean cohort of patients with ERS and BS who underwent implantable cardioverter defibri

• In our study we observed

  2019-04-26

  

  In our study we observed that MT produced a 50% improvement in the % area of tissues covered over that of H&E. It is possible that its three-in-one (trichrome) combination of dyes may be responsible for the large % area covered and high intensity measurement. This is in line with the report of Stree

• br VIII Si atendemos a que Pablo del Prado en

  2019-04-25

  

  VIII. Si atendemos tiotropium bromide que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca una normaliz

• Na segunda se o o

  2019-04-25

  

  Na segunda seção, o texto analisa wst-1 emergência dos pentecostais e neopentecostais como atores políticos a partir do cenário da Assembleia Constituinte, responsável pela elaboração da Constituição brasileira de 1988. Por conseguinte, averiguamos a forma como este segmento religioso construiu estr

• histone methyltransferase br Remote technologies The platfor

  2019-04-25

  

  Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c

• Your support for the official journal of the

  2019-04-25

  

  Your support for the , official journal of the Japan Heart Rhythm Society (JHRS) and the Asia Pacific Heart Rhythm Society (APHRS), is sincerely appreciated. We are pleased to announce that JOA has become an open access journal. Thus it is always available for readers online. All articles are acces

• There is a scarcity of rigorous and

  2019-04-25

  

  There is a scarcity of rigorous and reliable information about the occurrence, operation, and outcomes of immigration detention worldwide. New initiatives are needed to increase transparency and accountability and to build an evidence CA-074 Me for detention policy and practice. More comprehensive

• br Conflict of interest br

  2019-04-24

  

  Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep calculate the molarity episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some

• Friberg et al have indicated that the CHA DS

  2019-04-24

  

  Friberg et al. [17] have indicated that the CHA2DS2-VASc score is superior to the CHADS2 score in terms of stroke risk stratification, and the risk of stroke is extremely low among patients with a CHA2DS2-VASc score of 0 in whom antithrombotic therapy is not beneficial and may even increase the risk

• Two years later he complained of two ICD shocks

  2019-04-24

  

  Two years later, he complained of two ICD shocks during a dance party. The possibility of lead fracture or electromagnetic interference was completely excluded after several examinations. Intracardiac electrograms showed that all delivered shocks were inappropriate therapies due to TWOS. The R wave

• Autophagy can be generally divided into non selective

  2019-04-24

  

  Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein myc inh

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