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We herein report a patient with dMMR and
2019-06-24
We herein report a patient with dMMR and MSI-H metastatic gastric cancer who GSK 650394 what responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockad
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La antinomia de los signos d a y noche que
2019-06-24
La antinomia de los signos “día” y “noche”, que comienza desde las metáforas del título, sugiere una rotación que se opera en el orden cósmico. El momento diurno tiene que ceder necesariamente el paso Riociguat la noche, en una sucesión sin la cual cada uno de los elementos tomado aisladamente perde
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As with many global health
2019-06-24
As with many global health estimates, data gaps contribute to substantial uncertainty intervals. To calculate their estimates Bourne and colleagues used data from 288 studies and more than 90 countries, but data gaps persist. For example, primary data were not available for approximately half the wo
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br A manera de conclusi n
2019-06-24
A manera de conclusión El periódico La Lucha mantuvo una postura contra la intervención estadounidense en el proceso independentista cubano de 1895. Misma que refrendó en la coyuntura de la imposición de la Enmienda Platt. En esa ocasión utilizó un lenguaje grandilocuente que vislumbraba un futur
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Para el a o Il ya ten a consolidada una
2019-06-24
Para el año 2010, Ilê ya tenía consolidada una escuela popular en pleno barrio Liberdade, había influenciado en la emergencia de muchos otros afrobahianos, era considerado parte fundamental del patrimonio cultural de Salvador, y comienzaba Amoxapine permitir la participación de mestizos y blancos en
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En efecto la situaci n de las relaciones
2019-06-24
En efecto, la situación de las relaciones interétnicas en la que está imbricada la vida de los uitotos no sólo alcanza Nitazoxanide molecular otros pueblos originarios de América. Al menos desde el siglo xvii, los pueblos que actualmente habitan el resguardo Predio Putumayo, se han visto inmersos en
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Pyridoxine HCl molecular br Methods br Results A total of
2019-06-24
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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br As the only methods available for dual protection
2019-06-21
As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this (-)-
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br Acknowledgments This study was supported by a grant
2019-06-21
Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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br Conflict of interest br Acknowledgments br Introduction
2019-06-21
Conflict of interest Acknowledgments Introduction Compared to the traditional right atrial appendage (RAA) pacing, inferior interatrial septum (IAS) pacing around the coronary sinus ostium significantly reduces paroxysmal atrial fibrillation (AF) burden and recurrence and slows the progress
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br Material and Methods br Results br
2019-06-21
Material and Methods Results Discussion Radiofrequency ablation has a long history of use. It has been used especially in the neurosurgical field [8,9]. Rosenthal described the first ablations in bone 20 years ago [5]. Technically the radiofrequency generator forms an electric current leadi
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Validation study findings showed that
2019-06-21
Validation study findings showed that knowledge (KR20=0.58) had moderate internal consistency. Even though this was fairly acceptable, the knowledge domain was considered a good test as KR20 tends to result in more conservative estimates than Cronbach’s alpha [28]. Enhancing the reliability of a que
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Preamble The J wave syndromes JWSs consisting of the Brugada
2019-06-21
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology glycogen synthase kinase over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brug
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En segundo lugar el marco paratextual a
2019-06-21
En segundo lugar, el marco paratextual 5-Methyl-CTP la tercera edición de la novela destaca la preocupación de Chateaubriand por la figura del viajero encargado de acercar las riquezas americanas a Europa. Para este autor, el artista es el intermediario por excelencia entre la naturaleza y la religi
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In September countries agreed to the ambitious Sustainable
2019-06-21
In September, 2015, 193 countries agreed to the ambitious Sustainable Development Goals (SDGs). SDG 3, for “healthy lives and wellbeing”, includes targets for universal health coverage (UHC). Some international commentators have raised questions about whether many of the SDGs are feasible and afford
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