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A key observation of the present
2018-10-24
A key observation of the present study is that, contrary to a widespread practice, using multiple clones per individual can be very detrimental to the robustness of the study unless appropriate statistical methods are adopted. This represents a critical warning for the iPSC modeling field, since mos
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Deazaneplanocin br As this takes place we
2018-10-24
As this takes place, we have an easily testable relation meaning that it does not particularly matter in which order the independent regressors and the independent response components are lined when takes the diagonal form. With the OLS estimate and the mutual covariance matrix of the vector
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The reconstruction of mesons was done using their
2018-10-24
The reconstruction of φ-mesons was done using their decay channel into two charged kaons, φ→К+К−. Charged particle tracks were reconstructed in two main tracking detectors of the ALICE experiment: TPC (Time Projection Chamber) and ITS (Inner Tracking System). Because of the high multiplicity of part
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Since different boundary conditions correspond to different
2018-10-24
Since different boundary conditions correspond to different critical Grashof numbers, we used the concept of the critical parameter; it integrin signaling pathway was expressed by the ratio r=Gr / Grc. The behavior of the convective roll flow under normal and anomalous conditions determined by the
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At the IV III phase
2018-10-24
At the IV→III phase transition, the third harmonic coefficient γ3ω for nanostructured (as well as for bulk) potassium iodate (Fig. 3b) takes the minimal value, increasing by about four times with further heating. Thus, the temperature studies of the capacitance and the third harmonic coefficient hav
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Patients were eligible if they
2018-10-24
Patients were eligible if they were born in sub-Saharan Africa, were citizens of a sub-Saharan African country at birth, were between 18 and 59 years old, and had not been diagnosed with either HIV or hepatitis B (for the primary-care group) or had been diagnosed with HIV infection or chronic hepati
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Finally this analysis also contributes to our knowledge of
2018-10-24
Finally, this analysis also contributes to our knowledge of the determinants of limited physical functioning at older ages. The prevalence of functional limitations is increasing in many countries simply because of rapid AN-2728 aging. In some countries, such as the U.S. and Mexico, functional limi
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The variable gender is the most studied resource of the
2018-10-24
The variable ‘gender’ is the most studied resource of the voice in the literature on radio. Its advertising effectiveness has been studied, although with contradictory results (Wolin, 2003). With our study, we attempt to contribute by determining whether the prevalence of male spokespersons detected
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Here our ex vivo systemic analysis of
2018-10-23
Here, our ex vivo systemic analysis of the impact of extracellular Hb and LTA on whole WBC populations demonstrates that neutrophils are as sensitive as monocytes to metHb. Interestingly other leukocytes in the whole blood system seemed to dampen the synergistic effect of metHb+LTA on the neutrophil
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In recent years several groups have attempted
2018-10-23
In recent years several groups have attempted to identify specific signatures to distinguish between tuberculosis and sarcoidosis using transcriptomics or gene expression profilings (Koth et al., 2011; Maertzdorf et al., 2012; Berry et al., 2010). Yet, most of these methods led to the discovery of a
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In the clinic preconditioning is typically ascribed
2018-10-23
In the clinic, ‘preconditioning’ is typically ascribed to a transient mild stress followed by a recovery interval (Nishio et al., 2000; Stetler et al., 2014). Here we have applied this ahr inhibitor term in its broadest sense — i.e., a subtoxic cellular stress that can lead to a protective state (S
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br Introduction The Middle East respiratory syndrome coronav
2018-10-23
Introduction The Middle East respiratory syndrome coronavirus (MERS-CoV) is the only lineage C betacoronavirus known to infect humans (Annan et al., 2013; Anthony et al., 2013; van Boheemen et al., 2012). Similarly to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV infection ca
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The study by Kl ppel and colleagues
2018-10-23
The study by Klöppel and colleagues can decisively shape future functional neuroimaging research in HD and other neurodegenerative conditions, but we believe that there is much more to learn from this study. The rationale and design should also motivate psychiatric research, where there is still an
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br Funding and Role of Funder br Conflicts
2018-10-23
Funding and Role of Funder Conflicts of Interest Author Contributions Acknowledgements This work was supported by the Intramural Research Program, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. We thank Dr. Oksana Gavrilova for her excell
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Finally we searched the Allele Frequencies in Worldwide Popu
2018-10-23
Finally, we searched the “Allele*Frequencies in Worldwide Populations” (http://www.allelefrequencies.net/) website for known haplotypes related to the 6 discriminating alleles, within the 3 databases that we used. Haplotype information was available only for the SF database, as shown in Table 5. It
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